New Publication – Filling the Gaps in PFAS Detection: Integrating GC-MS Non-Targeted Analysis for Comprehensive Environmental Monitoring and Exposure Assessment

The newest publication from our BP4NTA members highlights the untapped potential of gas chromatography–mass spectrometry (GC-MS) in non-targeted analysis (NTA) of PFAS. While LC-MS has dominated PFAS studies, these findings show that GC-MS covers a complementary chemical space, crucial for identifying novel and volatile/semi-volatile PFAS that LC-MS may miss.

✅ Less than 10% of known PFAS chemistry is predicted to be amenable to typical LC-MS analysis.
✅ GC-NTA is essential for uncovering unknown PFAS in waste streams, incineration byproducts, air emissions, and consumer products.
✅ Collaboration is needed to overcome challenges and advance GC-NTA in environmental research.

We call on researchers, grantors, and stakeholders to recognize and invest in GC-NTA as a critical tool for fully understanding PFAS contamination. Let’s push the boundaries of PFAS research together!

Read more here: https://pubs.acs.org/doi/10.1021/acs.estlett.4c00930

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