April Meeting: Student Presenters

Our April 15 meeting will be at 12 pm US Eastern time. Our speakers will be four BP4NTA student members:

Noor Hamdan – Non-Target Identification of Organic Contaminants in Biosolid-Amended Soils Across the United States
William Fahy – Nontargeted kinetics for identifying environmental transformation products and pathways
Miranda Baker – Geolipidomics: Non-Targeted Analysis of Rapidly Heated Geologic Samples With Gas-Chromatography-Mass Spectrometry
Nathan Vinegas – Microplastics as Vectors of Organic Contaminants on Southern California Beaches: A TD/Py-GCxGC-TOFMS Study

Many thanks to those who submitted abstracts. 

SETAC North America – BP4NTA Session

Heads up! Best Practices for Non-Targeted Analysis (BP4NTA) is hosting a session at SETAC North America in Montreal this November. The session is titled “Non-targeted analysis and high-resolution mass spectrometry in environmental chemistry.” Keep an eye out when you’re submitting your abstracts!

As high-resolution mass spectrometry (HRMS) becomes more accessible, its application in environmental chemistry is exponentially increasing. Notably, HRMS has expanded the use of non-targeted analysis (NTA), enabling studies without a pre-defined list of analytes and/or that seek to detect and identify chemicals for which analytical standards may not be available. HRMS– based NTA is especially valuable for the discovery of new contaminants or transformation products, as well as “exposomic” research aiming to characterize a broad range of chemical mixtures across diverse environmental and biological matrices. While these methods are already producing valuable data and insights, challenges remain. For example, there is still need for improvements in study reproducibility and reporting practices, and expanding access to high‑quality spectral libraries, reference databases, and computational tools. This session will highlight recent advances in HRMS and NTA methods, discuss shortcomings that have yet to be addressed, and showcase novel environmental studies/applications utilizing these techniques.

Many thanks to Sara Nason, Carrie McDonough, Natalia Quinete, and Leenia Mukhopadhyay for putting this together!

March Speaker: Dr. Raees Ahmad

Our March 25 meeting will be at 12 pm US Eastern time.  Zoom link here and full information below. Our speaker will be Dr. Raees Ahmad, who will give a talk entitled: “Effect-directed Analysis of Hazardous Organic Chemicals Released from Ship Hull Hydroblasting Effluents and Their Emission to Marine Environments”.


Raees Ahmad is currently a Postdoctoral Research Scientist at The Connecticut Agricultural Experiment Station (CAES) in New Haven, Connecticut, USA. He holds undergraduate and master’s degree in Analytical Chemistry from the University of Malakand, Pakistan, where he focused on the photodegradation of dyes using molecularly imprinted polymers. He earned his Ph.D. in Analytical Chemistry from Kyungpook National University in Daegu, South Korea, where he developed an advanced effect-directed analysis (EDA) technique that integrates offline/online two-dimensional liquid chromatography–Mass Spectrometry with in-silico QSAR tools to identify both targeted and non-targeted contaminants in environmental matrices. At CAES, his research focuses on the suspect and non-targeted analysis of contaminants of emerging concern (CECs) and their transformation products in wastewater influent and effluent from treatment plants, as well as studying their accumulation and effects in plants.

Abstract: Hydroblasting operation on ship hulls is one of the major sources of chemical discharge into marine ecosystems, releasing biocides, binders, pigments, and additives. These activities contribute an estimated 6% to 17% of the daily biocide input from antifouling paint residues. However, most studies to date have focused primarily on target biocides, leaving other toxic chemical classes inadequately explored. This study applied effect-directed analysis to assess hydroblasting effluents using ultra-performance liquid chromatography coupled with high-resolution mass spectrometry. Toxicity screenings of both unfractionated and fractionated effluent samples revealed significant toxic effects on zebrafish embryos. Non-target analysis identified 68 compounds in the positive electrospray ionization mode and 25 compounds in the negative mode. Among these, specific toxic compounds responsible for the observed effects were identified within the fractions, with seven toxicants confirmed at Level 1 identification using reference standards. Quantitative analysis estimated the release of these toxicants to range from 0.16 to 121.83 g for the studied ship. When extrapolated to global hydroblasting operations, annual emissions of these toxic chemicals were estimated to be over 16 tons. These findings underscore the substantial environmental risks associated with hydroblasting effluents and emphasize the need for targeted mitigation strategies to reduce their ecological impact on marine ecosystems.

February Webinar: Dr. Oliver Fiehn

Please join us for our monthly meeting on February 18th, 12 pm EST. Dr. Oliver Fiehn will be presenting his talk, titled “MS/MS is not enough: retention time prediction and large-scale analyses in MassWiki.Metabolomics.us“.

Prof. Oliver Fiehn has pioneered developments and applications in metabolomics with over 500 publications to date with a current h-index 133, i10 index 484. He started his career as group leader at the Max-Planck Institute for Molecular Plant Physiology in Potsdam, Germany. Since 2004 he is faculty member in the College of Biological Sciences (MCB department) and Professor at the UC Davis Genome Center, overseeing his research laboratory and the satellite core service laboratory in metabolomics research. In 2012 he became the Director of the UC Davis West Coast Metabolomics Center, supervising 30 staff operating 16 mass spectrometers. To focus on large cohort studies and translational metabolomics, he has added the ThermoFisher Center of Excellence in Clinical Metabolomics at the UC Davis clinical campus in Sacramento, CA since 2021. In public outreach, the West Coast Metabolomics Center holds monthly public webinars, has a YouTube channel, a newsletter, invites international scholars to research visits and organizes two metabolomics professional courses per year.

January Monthly Meeting

Happy New Year BP4NTA!

We are ready to kick off 2026 with our first meeting on January 21 at 12 pm EST.  It has been designed to be both interactive and engaging and should provide attendees the opportunity to give valuable input to the steering committee.  It will also allow you to provide input on the current direction of the group and its subcommittees. Lastly, you will have some interaction in regard to the speakers and sectors you are most interested in hearing from.  We are currently forming the speaker list for 2026 and are seeking speakers that will provide professional value to our membership.

Please recall that nominations for the Kathy Peter Outstanding Service Award are still being accepted.  Please see the previous post for instructions on how to submit nominations.

Nominations open for the 2026 Kathy T. Peter BOS Award

Nominations are open for the 2026 Kathy T. Peter Memorial BP4NTA Outstanding Service Award! To nominate a deserving BP4NTA member, please fill out this form by February 17, 2026.

The BP4NTA Outstanding Service Award recognizes an individual for their outstanding contributions and service to BP4NTA in support of the BP4NTA mission. Such contributions may include, for example: enabling the inclusion and integration of diverse voices and perspectives in BP4NTA products and projects through exceptional leadership; dedicated involvement in and visionary contributions to BP4NTA operations, committees, and/or scientific products; enthusiastic recruitment and mentorship of BP4NTA members (particularly early-career scientists and stakeholder/non-researcher members), fostering their participation in BP4NTA committees and projects; or committed advocacy to raise awareness of BP4NTA goals and products within the larger NTA community and promote external collaborations.  Selection is based on the quality of the individual’s contributions to BP4NTA and the impact of their service on the quality of BP4NTA operations and/or projects (75%), and the quantity of service contributions to BP4NTA, including the time spent on service to BP4NTA (25%).

This award is named in memory of Kathy Peter, who was a highly active and influential BP4NTA member. She tragically passed away in late 2024. An article highlighting her career achievements, including her work with BP4NTA was recently published in ES&T. Help us continue her legacy by nominating deserving folks for this year’s award.

November Speaker: Dr. Michael Rush

Please join us for our monthly meeting on November 18th, 12 pm EST. Our speaker, Michael Rush, is a Distinguished Chemist at Edwards Lifesciences, specializing in advanced mass spectrometry and non-target analysis. As co-chair of the BP4NTA E&L technical subcommittee, Michael drives best practices and workflow harmonization to improve reproducibility and innovation in chemical characterization

Abstract: Non-targeted analysis (NTA) continues to evolve as a critical tool for comprehensive chemical characterization, particularly in complex matrices such as medical device extractables and leachables (E&L). Recent work, including our publication in Analytical Chemistry (DOI: 10.1021/acs.analchem.5c04247), demonstrates how advanced mass spectrometric workflows can improve reliability and reproducibility in E&L studies. This research highlights issues with quantitation strategies for medical device biocompatibility. 

A second focus of this presentation will be communicating confidence in identifications—a cornerstone for regulatory acceptance and scientific transparency. We will explore the ISO10993-18 and FDA draft guidance in respect to how Edwards reports confidence levels in identifications.  

Finally, we will provide an update on the BP4NTA E&L Technical Subcommittee, which aims to harmonize best practices for NTA in E&L testing. The subcommittee’s initiatives include integrating regulatory guidance, promoting collaboration across industry and academia, and developing educational resources to support newcomers and experienced practitioners alike. These efforts seek to advance reproducibility, foster innovation, and strengthen community standards for non-targeted workflows.

Postdoctoral Scientist Position at the Connecticut Agricultural Experiment Station (CAES)

Drug abuse is a major problem affecting individuals and communities worldwide, but it is difficult to study. Analysis of untreated wastewater is an increasingly common technique for assessing drug use on a community scale. We are investigating drug abuse in cities across Connecticut by combining wastewater analysis with street level data collection in collaboration with local harm reduction groups and the Yale School of Public Health. The postdoc hired for this project will be responsible for planning and executing wastewater sample collection, conducting wastewater analysis using mass spectrometry techniques, and communicating with collaborators across disciplines to share data and publish meaningful results. We are seeking a recent Ph.D. with training in environmental engineering, analytical chemistry, environmental health, or a closely related field. Preference will be given to candidates with experience in the following areas:

  • Interdisciplinary collaboration and communication
  • Field sampling of wastewater systems
  • LC-MS analysis (including targeted and non-targeted methods) and sample preparation for analysis of organic contaminants in complex matrices
  • Complex, multivariable statistics
  • GIS software

Candidates must have a valid U.S. driver’s license and be confident driving to different cities for sample collection. The candidate should demonstrate enthusiasm for the projects, a willingness to learn, a commitment to work cooperatively, and must be able to work independently and as part of a team. Strong written and verbal communication skills are required. A significant record of productivity as demonstrated through refereed publications is preferred. The appointment is for 1.5 years, with potential extension subject to performance and funding availability. The starting salary is $56,982/yr with competitive medical and dental benefits. The ideal start date is November 1, 2025.

Interested candidates should submit the following documents electronically:

  1. A letter of application describing your interest in the position, research interests and career goals, and a brief overview explaining how your research experience will help you succeed with the position duties.
  2. A Curriculum Vitae
  3. The names and contact information (including email addresses) for three professional references.

Please send the above materials to Sara Nason (sara.nason@ct.gov) and Anuja Bharadwaj (anuja.bharadwaj@ct.gov). Review of applicants will begin ASAP and continue until a suitable candidate is found. Candidates can contact Sara with any questions about the position.

The Connecticut Agricultural Experiment Station is the nation’s first state Agricultural Experiment Station, founded in 1875. The main campus is located in New Haven, Connecticut. The CAES also encompasses a 75-acre research farm in Hamden, a satellite research facility and farm in East Windsor, and a research farm in Griswold. The CAES is a state-supported scientific research institution dedicated to improving the food, health, environment, and well-being of Connecticut residents.

September Meeting: Dr. Jeremy Koelmel

Please join us for our monthly meeting on September 16th, 12 pm EST. Our featured speaker is Jeremy Koelmel, an Associate Research Scientist in Epidemiology at the Yale School of Public Health, who will present on “Non-Targeted Analysis in Exposomics: Global Perspectives from the NEXUS International Survey.”

Abstract: In this presentation, we will discuss the essential role of non-targeted analysis in exposomics, and assess the multi-omics landscape of measurement science covering: lipidomics, metabolomics, xenobiotics, adductomics, and other approaches. Results are based on a survey conducted with over 150 participants (including a large presence of BP4NTA members!) and consisting of over 200 questions, giving both high-level and granular information pertaining to multi-omics analysis. Results we will cover include the types of matrices analyzed, instrumentation and software used, and chemical coverage. Community strategies in sample preparation, acquisition, and data-processing methods will also be discussed.  Beyond the survey we will also discuss other Network for EXposomics in the U.S. (NEXUS) initiatives including the development of training materials for non-targeted analysis and exposomics and a user-friendly platform for processing non-targeted analysis data. NEXUS is a U24 Center for Exposome Research Coordination. NEXUS serves the broad biomedical research community by coordinating and advancing exposome research. The Center engages existing and ongoing exposome initiatives around the globe to promote methodological advancement and best practices, provide training and education, and foster national and international collaborations.

Please email us if you are having trouble accessing the Zoom meeting.