Please join us for our monthly meeting on August 19th, 12 pm EST. Our featured speaker is David Weil, a Master Applications Scientist at Agilent who will present on “Challenges and Best Practices for Extractable and Leachable Nontargeted Analysis”
Abstract: Extractable Leachable (E&L) analysis is just one of the many application areas that currently utilize nontargeted data analysis workflows. As pointed out in the recent publication from the BP4NTA group, E&L analysis faces many challenges starting with the complex nature of polymer extract samples and ending with compound identification. The talk will start by giving a brief overview of E&L analysis; then overview the regulatory landscape and recent push for standardization, emphasize how “good” chromatography matters to reduce false positives and enhance separation/sensitivity and wrap up by talking about methods to improve compound identification leveraging third-party online content. During the talk I will be give “Tips and Tricks” on ways to improve the quality of data being collected (MS and MSMS modes) and examples of where NTA required manual intervention.
Please email us if you are having trouble accessing the Zoom meeting.