The only NTA method info I have found from Waters is their PFAS NTA Applications Note that uses a Xevo G2-XS QToF MS. However, it sounds like you are trying to do something more inclusive than PFAS. The note can be found at https://www.waters.com/content/dam/waters/en/app-notes/2021/720007184/720007184-en.pdf (Application Note: Approaches to Non-targeted Analyses of Per- and Polyfluoroalkyl Substances (PFAS) in Environmental Samples)