Session: Application of High Resolution-Accurate Mass (HR-AM) Methods, Workflows, and Software Tools for Transformation Product Identification
Session chairs: Amanda Brennan and Denise MacMillan
Description: The properties of contaminants can transform due to environmental and/or biological interactions and reactions; however, the occurrence, fate, and toxicity of transformation products (TPs) are largely unknown. Investigation of TPs from emerging contaminants is critical to better inform environmental and human health risk assessments by filling data gaps. Non-targeted analysis (NTA) and HR-AM are important tools for the identification of TPs of emerging concern. However, identification is still a challenge due to 1) the difficulty in predicting transformation pathways for environmentally relevant chemicals, 2) abundance and complexity of data generated with NTA and HR-AM techniques, 3) complexity of matrices, 4) chemical variety, and 5) lack of standards.
This platform and poster session will focus on (but is not limited to): identification and occurrence of novel biological and environmental TPs; development, advances, and availability of analytical and computational tools (e.g., predictive tools and/or databases) and workflows for identification; and application to environmental and biological matrices for any class of emerging organic contaminants, including cannabinoid pesticides and per- and polyfluoroalkyl substances (PFAS).